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Venture capital firm Benchmark Capital is suing former Uber Chief Executive Officer Travis Kalanick to force him off the board of the ride-services company and rescind his ability to fill three board seats, according to the lawsuit.The lawsuit filed Thursday accuses Kalanick of concealing a range of misdeeds from the board new balance pour femme and scheming to retain power at the company even after he was forced to resign as chief execu adidas campus damen tive of Uber in June following a series of scandals.The company is currently seeking a new CEO, a search that has proved difficult.Benchmark's lawsuit marks a rare instance of a Silicon Valley investor suing the central figure at one of its own campus adidas start-ups. The well-regarded venture firm was an early investor in Uber and said in the lawsuit that it owns 13 per cent of Uber and controls 20 per cent of the voting power.8 uber-rich celebs with frugal lifestyle habitsKalanick issued a statement calling the lawsuit "completely without merit and riddled with lies and false allegation The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new University at Buffalo-led study.The research sought to understand how P. gingivalis colonizes the mouth. The pat nike dunken low hogen is air force 1 unable to produce its own growth molecules until it achieves a large population in the oral microbiome (the community of microorganisms that live on dunk nike low and inside the body).The answer: It borrows growth molecules from V. parvula, a common yet harmless bacteria in the mouth whose growth is not population dependent.In a healthy mouth, P. gingivalis makes up a miniscule amount of the bacteria in the oral microbiome and cannot replicate. But if dental plaque is allowed to grow unchecked due to poor oral hygiene, V. parvula will multiply and eventually produce enough growth molec

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KARACHI:Pakistan ugg fellboots batsman Babar Azam鈥檚 second consecutive ODI century and a swashbuckling 90 by Shoaib Malik propelled the Men in Green to a hugely impressive score of 337-5 in the second ODI of the three-match series against the West Indies.Batting first on a typical Sharjah belter, the Pakistan batsmen took full advantage of some loose offerings by the tourists despite losing openers Azhar Ali and Sharjeel Khan early in the innings.Babar scored a master newbalance 530 ful 123 off 126 balls in an innings that bettered his sublime 120-run knock in the first ODI of the series on Friday 鈥?the Lahore youngster hit nine fours and a solitary six in his brilliant batting effort.Malik bashed six sixes, including three on three successive balls off Suleiman Benn, during his 169-run third-wicket alliance with Baba adidas campus blau r; the right-hander perished for 90 off 84 balls. His innings also included three fours.Perseverance the key, says centurion AzamSarfraz Ahmed upped the ante towards the end of the innings with a 47-ba Scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) have reported a major advance in understanding the biological chemistry of radioactive metals, opening up new avenues of research into strategies for remedial action in the event of possible human exposure to nuclear contaminants.Research led by Berkeley Lab鈥檚 Rebecca Abergel, working with the Fred Hutchinson Cancer Research Center in Seattle, has found that plutonium, americium, and other actinides can be transported into cells by an antibacterial protein called siderocalin, which is normally involved in sequestering iron.Their results were published online recently in a paper titled, 鈥淪iderocalin-mediated recognition, sensitization, and cellular uptake of actinides.鈥?The paper contains several other findings and achievements, including characterization of the first ever protein structures containing transuranic asic schuh elements and how use of the protein can sensitize the metal鈥檚 lumines yeezys cence, which could lead nike dunk high to potential me

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Traditionally, prostate tumors have been found through so-called blind biopsies, in which tissue samples are taken systematically from the entire prostate in the hopes of locating a piece of tumor 鈥?a technique that dates back to the 1980s. But the cancer now appears detectable by direct sampling of tumor spots found using magnetic resonance imaging, or MRI, in combination with real-time ultrasound, the researchers say.The findin nb gs are published Dec. 10 in the early online edition of the Journal of Urology and are scheduled for print publication in the journal's January issue.The UCLA study ind yeezy 500 icates that the MRI鈥搖ltr converse asound fusion biopsy, which is much more accurate than a conventional blind biopsy, may lead to a reduction in the number of prostate biopsies performed and could allow for the early detection of serious prostate cancers.The study involved 171 men who were either undergoing active surveillance to monitor slow-growing prostate cancers or who, despite prior negative biopsies STOCKHOLM:Norwegian artist Tone Bjordam was moved to tears when she heard an eminent Swedish scientist explain the relationships between nature, society and the economy at a 2013 workshop in Uruguay.Displaying a diagram of three concentric circles, with the economy in the middle an adidas sambarose d nature on the outside, Carl Folke, science director of the Stockholm Resilience Centre, argued that if the economy collapses, society and nature will likely survive, and if society implodes, then nature can stay intact. But if nature nb balance - the planet's ecosystems, wildlife and climate - descend into chaos, then so will the society and economy it supports."He said, 'I have never seen anyone react so emotionally to something as dry and boring as this!'," recalled Bjordam at a recent conference in Stockholm where scientists discus stanley-cup sed ways to keep the planet and its inhabitants healthy and in balance.Scientists claim discovery of massive black hole in Milky WayIn a hall next door hung the inspiration from her Latin

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The Personalized Medicine Coalition (PMC) has announced that Patrick J. Balthrop, president and CEO of Luminex Corporation was elected to the Coalition's board of directors for a three-year term."Pat will be a strong addition to the Coalition. As CEO of Luminex, an important player in the field of personalized medicine, his dunk high company has been on the forefront of developing innovative products that assist patients, including instruments and assays that make health care faster, more accurate and affordable. His leadership, notably in navigating the regulatory arena, will serve PMC well," said Stafford O'Kelly, former president of Abbott Molecular and current chairman of the PMC.Mr. Balthrop joined Luminex Corporation as President an converse d CEO in May of 2004. Prior to joinin air force1 g Luminex, Mr. Balthrop was employed by Fisher Scientific International as President of Fisher Healthcare for two years.He spent 20 years in the medical devices and diagnostics divisions at Abbott Laboratories, successfully t KARACHI:We will make Karachi the cleanest city in Asia, vowed Muttahida Qaumi Movement (MQM) Pakistan convener Farooq Sattar. He said that the party has pledged to turn certain union councils ( adidas samba sale UCs) in the city into model UCs.He said that for that purpose they have selected a few UCs in Korangi and Malir and Landhi districts and another in Shah Faisal. He was speaking to the media during the inauguration of a project to pave 100 streets with concrete blocks in 100 days in UC-6 in District Korangi. This project is part of the mayor's 100-day cleanliness campaign.We have to make Karachi neat and clean, says CMHe stressed that in one UC, a hundred streets will be paved with concrete blocks and sanitation and cleanliness in the UC will also be improved. Sattar a adidas samba adidas lso claimed that in every model UC, a school and dispensary will also be constructed."We have decided that we won't look back from her adidas sambarose e and without any resources and powers we will turn Karachi's UCs into model UCs, one by one," he a

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AbstractThe discrepancy between the X-ray and NMR structures of Mycobacterium tuberculosis peptidyl-tRNA hydrolase in relation to the functionally important plasticity of the molecule led to molecular dynamics simulations. T jordan he X-ray and the NMR studies along with the simulations indicated an inverse correlation between crowding and molecular air force 1 herren volume. A detailed comparison of proteins for which X-ray and the NMR structures appears to confirm this jordan schuhe correlation. In consonance with the reported results of the investigations in cellular compartments and aqueous solution, the comparison indicates that the crowding results in compaction of the molecule as well as change in its shape, which could specifically involve regions of the molecule important in function. Crowding could thus influence the action of proteins through modulation of the functionally important plasticity of the molecule.The article is published online in the Journal of Biosciences and is free to access. PESHAWAR:Some 94 per cent of people displaced due to militancy and military operation in different agencies of the Federally Administered Tribal Areas (Fata) have returned to their homes.?€?Only 6 per cent of the people ?€? mostly belonging to adidas samba hombre South and campus adidas femme North Waziristan agencies ?€? are yet to resettle due to security concerns or unavailability of facilities,?€? said Fata Disaster Management Authority (FDMA) Director General Khalid Khan on Wednesday.Speaking after adidas samba rose a ceremony held with regard to the signing of a memorandum of understating (MoU) between FDMA and UNHCR at the Fata Secretariat here, Khalid said most of Pakistan?€?s internally displaced people (IDPs) had returned to their homes in tribal areas.?€?Around 3, 50,000 verified and 2,00,000 unverified families of tribal areas have returned to their areas, while 49,000 families of Data Khel and adjacent areas are yet to return due to security situation and unavailability of basic facilities,?€? he said.75,000 IDP families rehabilitated, says re

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Amyotrophic lateral sclerosis (ALS) is a severe, fatal neurodegenerative disorder causing loss of motor neurons and voluntary muscle action. While mouse studies have identified potential treatments, these drugs have typically done very poorly in human trials. Researchers at Boston Children's Hospital, working in collaboration with Pfizer, now report a high-throughput target and drug discovery platform using motor neurons made from ALS patients. Using the platform, they confirmed two known targets and identified an existing class of drugs -- agonists to the dopamine D2 receptor -- as potential novel treatments.The researchers, led by Clifford Woolf, MD, PhD, director of the F.M. Kirby Neurobiology Center at Boston Childr [url=https://www.adidas-yeezy.de]yeezys 350[/url] en's, and first authors Xuan Huang, PhD, and Kasper Roet, PhD, in Woolf's lab, [url=https://www.adidas-yeezys.com.mx]yeezy[/url] describe the platform and their findings June 8 in the journalCell Reports.To create the motor neurons used for drug screening, the team used induced pluripotent stem cells, mad [url=https://www.nbbalance.de]new balance damen[/url] e by the lab of Dwellers of Lahore city have expressed mixed reactions over the Supreme Court (SC) verdict in the Panama case by distributing sweets and burning tires on main city roads on Friday.Workers and supporters of both opposition and ruling parties took to the street to either condemn or celebrate the apex court decision in which former prime minister Nawaz Sharif had been disqualified for hiding his real a [url=https://www.nbbalance.es]nb 9060[/url] ssets values.Pakistan Tehreek-e-Insaf (PTI) workers and supporters celebrated the SCP decision by distributing sweets and dancing on drum beats. A large number of PTI work [url=https://www.nbbalance.fr]new balance grise[/url] ers, including women, gathered here at PTI Chairman鈥檚 Secretariat in Garden Town and various other areas in the city to celebrate victory in the Panama case. PTI workers were holding party flags and portraits of the party Chairman Imran Khan, while chanting slogans in favour of their leaders and the apex [url=https://www.inkwiz.se]ugg ultra mini[/url] court. A PTI supporter dancing on a road following Panamagate verdict. PHOTO IZHAR ULLAH

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An international team of researchers at the University of Cambridge, funded principally by the Wellcome Trust, studied two individuals who were first identified on the basis of abnormal thyroid function, but subsequently found to also have low levels of selenium in the body.Selenium is found in relatively high doses in foods such as Brazil nuts. Although toxic in large amounts, as a trace element it is essential to cellular functions in animals, including humans. In the body, it is incorporated as the amino acid selenocysteine into some proteins (known as selenoproteins).The i nike sb dunk ndividuals identified by the researchers were found to have a particular variant of the gene SECISBP2 which meant that their bodies were unable to produce most of the 25 known human selenoproteins. As a consequence of selenoprotein deficiencies in particular tissues, they developed disorders such as male infertility and muscular dystrop new balance 550 hy (muscle weakness).Other feature yeezy boost s of the disorder were due to loss of a subse PARIS:After dazzling on his first appearance in a Paris Saint-Germain shirt, Neymar is in line to make his home debut for his new club against Toulouse adidas campus 80s on Sunday.The world's most expensive player scored one goal and set up another in a starring performance as PSG beat Guingamp 3-0 away in Brittany last weekend to maintain their perfect start to the new French season.The 鈧?22 million signing from Barcelona has already taken to the pitch at PSG's Parc des Princes for an unveiling before their 2-0 win over Amiens there on the opening day of the campaign.Neymar pledges glory for PSG after setting new transfer r new balance homme ecordBut he was not registered in time to play in that match so PSG's home support are eager to watch the 25-year-old run out against Toulouse. In contrast, the opposition coach is rather more apprehensive."We are going to Paris to adidas samba rose defend first of all 鈥?that is for sure. We will park the bus," said Pascal Dupraz, whose team did beat PSG at home and drew away last season en route to a

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Geron Corporationhas announced two grant awards to the nike dunk nike University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.The awards, totalling 拢3.6 million (US$7.2 million) over two years, follow on from a collaboration set up in August 2006 between Geron and the University of Edinburgh to develop hESC-derived hepatocytes for the treatment of liver failure and for use in cell-based assays, as well as to develop osteoblasts and chondrocytes for the treatment of musculoskeletal disorders such as osteoporosis, bone fractures and osteoarthritis.The grants relate to preclinical safety and efficacy studies of three therapeutic cell types derived from human embryonic stem cells (hESCs). The projects are led by Dr. Brendon Noble and Prof. John Iredale at the University of Edinburgh鈥檚 MRC Centre for Regenerative Medicine.鈥淭hese are the first grants we have yeezy slides awarded that use human embryonic stem cells,鈥?said Sir Richard Syke yeezys slide s, Chairman Following the example set by Paul the Octopus, Watson the sea-lion hopes his nose for winners will bring him international stardom - and a few extra fish - as he predicts the outcome of France's games in the Euro soccer cha newbalance 9060 m adidas samba blanche pionship.Euro 2016: Payet stuns Romania as France emerge victorious in tournament openerWeighing in at a sprightly 350 kg (771.62 lb), the middle-aged mammal, residing in a zoo in the eastern French town of Amneville, accurately forecast France's passage to the quarter-finals of the 2014 World Cup, calling each game right until the French were knocked out 1-0 by Germany.Ten Euro 2016 fans to face trial while 150 Russians escape arrest: prosecutorHe signals his choice by picking up one of three ice-boxes bearing the flags of the rival teams and a "draw" sign.Zoo keeper Pablo Joury hopes Watson will be a worthy s adidas campus noir uccessor to the German octopus, who accurately predicted Germany's 2010 World Cup run and became a celebrity before dying a few months later.US warns Euro 201

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How does our memory work and how can we optimize its mechanisms on a daily basis? This question is at the heart of many neuroscience research projects. Among the brain structures examined to better understand memory mechanisms, the reward s yeezy 350 ystem is now at the center of investigations. Through the examination of brain activity in healthy human subjects, scientists from yeezy 700 the University of Geneva (UNIGE) have highlighted the lasting positive effect of a reward 鈥?monetary, in this case 鈥?on the ability of individuals to retain a variety of information. Moreover, and much more surprisingly, the research team demonstrated that the average accumulation of reward should be neither too asic gels small nor too large. By ensuring an effective neural dialogue between the reward circuit and the memory circuit, this delicate balance allows the proper encoding of memories in our brain.Empirically, it seems quite logical that obtaining a reward can improve the memories associated with it. But what are the brain LAHORE:Pakistan Tehreek-i-Insaf (PTI) leader Chaudhry Sarwar said on Monday the party would take to the streets if the Panama Papers scandal was not probed fairly.Speaking at PTI鈥檚 youth convention, titled Future Leaders鈥?Network, Sarwar accused the government of delaying the matter regarding finalisation of terms of reference (ToRs) for probing the scandal.PTI leaders Mali stanleycup k Zaheer Abbas Khokhar, Mian Hammad Azhar and Umar Dar were also present on ugg fellboots the occasion.Panama papers: Govt running out of options: Sarwar聽鈥淭he new balance uomo government should not be afraid of accountability if its hands are clean,鈥?Sarwar said. He demanded that the government immediately solve the matter related to the ToRs. 鈥淚f the government keeps delaying the issue, that will be detrimental for the democratic process and for the government.鈥?He said PTI leaders were on the same page in demanding accountability of the corrupt.Sarwar said the government must realise that the nation stood united against corruption. It wants a [f

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Scientists and activists alike have been looking for a solution to the problem of aquatic nutrient pollution. Now one group reports in Environmental Science & Technology that ribbed mussels are up to the clean-up challenge.When it comes to nutrients, like nitrogen and phosphorus, too much of a good thing can be bad. These nutrients end up in rivers and streams a nike dunk sb s the result of human activities and can cause algal blooms, loss of seagrass and low oxygen levels, which can lead to large numbers of fish and other organisms dying. Many studies have examined how to prevent this runoff, but not much attentio nike dunk low n has been paid to removing the nutrients from the water. Some agencies have started programs to do this, and they are using shellfish to filter out unwanted substances. Geukensia demissa, known as the ribbed mussel, is one type of shellfish proposed for these programs. This mussel lives in various ha adidas yeezys bitats and can filter bacteria, microalgae, and detritus containing nutrients and cont AUSTIN, TEXAS:The Southern P new balance pour femme overty Law Center said in a report released on Wednesday that hate groups in the United Stat adidas samba donna es proliferated in 2016 as Donald Trump's bid for the US presidency energised the radical right."Trump鈥檚 run for office electrified the radical right, which saw in him a champion of the idea that America is fundamentally a white man鈥檚 country," the Southern Poverty Law Center said.The nonprofit civil rights organisation said in its annual census of hate groups that anti-M nb 1080 uslim groups nearly tripled to 101 in 2016 from 34 in 2015. It said hate groups in the United States numbered 917 last year compared with 892 in 2015.British man鈥檚 charity donations frozen by US as his name is 鈥業slam鈥橳he White House did not respond to a request for comment.At a news conference with Israeli Prime Minister Benjamin Netanyahu on Wednesday, President Trump was asked to comment on an increase in anti-Semitic incidents in the United States and to respond to those in the US Jewish community,

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There is good evidence that polluted air increases the ri yeezy slide sk of respiratory problems such as asthma 鈥?as well as organ inflammation, worsening of diabetes and other life-threatening conditions.But new research suggests air pollution can also fuel something else: chronic kidney disease, or CKD, which occurs when a person鈥檚 kidneys become damaged or cannot filter blood properly.Recently published in PLOS One, a University of Michigan s yeezy foam tudy highlights the lesser-known connection.鈥淪imilar to smoking, air pollution contains harmful toxins that can directly affect the kidneys,鈥?says Jennifer Bragg-Gresham, M.S., Ph.D., a Michigan Medicine epidemiologist yeezy 500 and the study鈥檚 lead author.鈥淜idneys have a large volume of blood flowing through them, and if anything harms the circulatory system, the kidneys will be the first to sense those effects.鈥漃eople with diabetes, obesity, high blood pressure or heart disease are at increased risk of developing CKD. Which is why high-risk patients who live in heav MADRID:French striker Antoine Griezmann kickst adidas samba adidas arted Atletico Madrid's La Liga campaign with two goals and an assist as a 4-0 rout at Celta Vigo gave them a much-needed boost on Saturday.It was a first win of the current La Liga season after they were held by promoted Alaves and Leganes in their opening two league games.The Champions League runner-up were outplayed for the first-half in Vigo on Saturday too, as Josep Sense and Theo Bongonda missed great chances.Transfer ban won't stop Real winning: ZidaneBut Atletico's luck turned when Koke met Griezmann's fine cross eight minutes into the second-half to give the visitors the lead before Euro 2016's top scorer Griezmann headed home his first two goals of the season in the final 20 minutes, whereas Angel Correa added a fourth two minutes from time.Celta who once again nb balance paid for their chances in promising first-half performance, and paid the price in the end as they are yet to pick up their first points of th adidas campus verte e season.Mourinho denies Guardi

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Published inClinical Cancer Research1, a journal of the American Association for Cancer Research (AACR), preliminary results (part 1) of a two-part, first-in-human, open-label and multicenter study show that monotherapy with JNJ-64619178颅鈥攁 novel, selective inhibitor of protein arginine methyltransferase 5 (PRMT5)鈥攄emonstrated manageable dose-dependent toxicity and achieved preliminary antitumor activity in patie new balance 9060 nts with advanced malignant solid tumors or B cell non-Hodgkin lymphomas (NHL) who previously received or were ineligible for standard treatment options.鈥淭heprotein arg adidas yeezy inine methyltransferase 5 is overexpressed in several human cancers and has been shown to have oncogenic properties via epigenetic mechanisms. PRMT5 promotes the proliferation, invasion and migration of cancer cells, and therefore represents a promising target in cancer drug disco dunk low very,鈥漮bserves Irene Bra帽a, Principal Investigator of the Vall d鈥橦ebron Institute of Oncology鈥檚 (VHIO) Head and Neck Cancer Group, CORE Until recently, the world was accustomed to negative news from Paki adidas campus 80s stan, ranging from rising debt to terrorism attacks and from political instability newbalance 9060 to border tensions. This however is changing, with Pakistan seemingly set on a new growth trajectory. Not only did the KSE-100 index cross the landmark 50,000 threshold recently, but on many other fronts it has been a bearer of good news, such as improved macro-economic outlook, major foreign investments, China-Pakistan Economic Corridor expected to bring significant trade flows and a vibrant startup scene taking off.Pakistan predicted to be world鈥檚 fastest-growing Muslim economy in 2017While the successful closure of IMF鈥檚 programme itself was adidas campus verde a testament that Pakistan has done well on macroeconomic stability, there are a number of other forecasts about the country鈥檚 positive economic outlook. The Asian Development Bank recently raised the growth projections for 2017 to 5.2 per cent, while The Economist termed Pakistan the fastest-growin

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Circulating tumor cells (CTCs) are cells tha adidas yeezys t break away from a tumor and move through a cancer patient鈥檚 bloodstream. Single CTCs are extremely rare, typically fewer than 1 in 1 billion cells. These cells can take up residence in distant organs, and researchers believe this is one mode by which cancer spreads.Even less common than single CTCs are small groups of CTCs, or clusters. While the existence of CTC clusters has been known for more than 50 years, their preval dunk low ence in the blood as well as their role in metastasis has not been thoroughly investigated, mostly because they are so elusive. However, recent advances in biomedical technologies that enable researchers to capture single CTCs have renewed interest in CTC clusters, which are occasionally captured along with single CTCs.Now, researchers led by Mehmet Toner, Ph.D., report the development of a novel microfluidic c nike dunks high hip that is specifically designed for the efficient capture of CTC clusters from whole, unprocessed blood.鈥淰ery li OKARA:As calls for his resignation r newbalance ose to a crescendo in the aftermath of the Panamagate verdict, Prime Minister Nawaz Sharif on Saturday struck a defiant note, telling his political rivals that he would never step aside.Sharif mocked the calls for his resignation, led by the Pakistan Tehreek-e-Insaf (PTI), saying that Imran Khan鈥檚 party has no other business than calling for his resignation. 鈥淵ou鈥檙e not suited for politics. You don鈥檛 know how to run the country. Go, play cricket,鈥?the premie adidas campus grise r said while addressing the cricketer-turned-politician.He was speaking at a public meeting in Okara鈥檚 football ground 鈥?a day after his political arch-nemesis, Imran Khan, addressed a rally in Islamabad where he had renewed his call for Premier Sharif to step down. He also mocked Imran鈥檚 rally calling it a 鈥榯iny gathering鈥?Nawaz comes out all guns blazing against Sindh govtThe uggs hausschuhe prime minister blamed his predecessors for the chronic power outages in the country. 鈥淧eople must hold those politicians

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Researchers at the Salk Institute have healed injured hearts of livin yeezys kaufen g mice by r yeezy 500 eactivating long dormant molecular machinery found in the animals鈥?cells, a finding that could help pave the way to new therapies for heart disorders in humans.The new results, published November 6, 2014 in the journal Cell Stem Cell, suggest that although adult mammals don鈥檛 normally regenerate damaged tissue, they may retain a latent ability as a holdover, like their distant ancestors on the evolutionary tree. When the Salk researchers blocked four molecules thought to suppress these programs for re yeezy generating organs, they saw a drastic improvement in heart regeneration and healing in the mice.The findings provide proof-of-concept for a new type of clinical treatment in the fight against heart disease, which kills about 600,000 people each year in the United States-more than AIDS and all cancer types combined, according to the U.S. Centers for Disease Control and Prevention.鈥淥rgan regeneration is a fascina RAWALPINDI:The Rawalpindi Development Authority (RDA) has adidas samba schuhe prepared a Rs5.223 billion budget for the current year with an eye on the provincial government for contributions through special gran adidas campus uomo ts, documents available with The Express Tribune show.According to the documents, the total income of the authori uggs ty has been estimated at Rs5,223.972 million, while total expenditure is estimated at Rs5,222.864 million, for a small surplus of Rs1.108 million.The budget would be presented before the RDA finance sub-committee for formal approval. Under RDA rules, the governing body was to approve and pass the annual budget, but it is presently non-functional.Budget documents show the RDA expects to generate Rs749.966 million from its own resources, and expects to receive over Rs4.474 billion from the Punjab government through special grants.Documents show that the authority would actually put together Rs100.212 million from its own revenue, including Rs3.5 million from 鈥渕iscellaneous sources鈥? with

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In a new analysis, researchers have shed light on these hereditary elements across 12 cancer types 鈥?showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well-known breast cancer susceptibility genes,BRCA1 and BRCA2.The investigators analyzed genetic information from more than 4,000 cancer cases included in The Cancer Genome Atlas project, an initiative funded by the National Institutes of Health (NIH) to unravel the genetic basis of cancer.鈥淚n ge dunk panda neral, we have known that ovarian and breast cancers have a significant inherited component, and others, such as acute myeloid leukemia a yeezy nd lung cancer, have a much smaller yeezy sneakers inherited genetic contribution,鈥?said senior author Li Ding, PhD, associate professor of medicine and assistant director of the McDonnell Genome Institute at Washington University. 鈥淏ut this is the first time on a large scale that we鈥檝e been able to pinpoint gene culprits or even th FAISALABAD:In a bid to enhance bilateral relations, Iranian Consul General Mohammad Hussain Bani Asadi has said the annual meeting of the Pak-Iran Joi uggs hausschuhe nt Econo adidas samba mic Commission will be held in Tehran immediately after Ramazan in which tariff issues would be resolved.Speaking to businessmen at the Faisalabad Chamber of Commerce and Industry (FCCI) on Monday, Asadi said after Iranian President Hasan Rouhani鈥檚 visit to Pakistan, he was optimistic that bilateral trade would increase up to $5 billion.He pointed out that a trade delegation of the Lahore Chamber of Comme ugg rce and Industry had visited Iran and similarly the FCCI should also send its delegation to explore and exploit the available trade opportunities.鈥淚ran is a big market for textile products and hence exporters belonging to Faisalabad should exploit this,鈥?he said and stressed the need for exchange of trade delegations and holding exhibitions on a reciprocal basis.The consul general said some Pakistani businessmen were already worki

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The National Institutes of Health will award funds to support the next phase of its Tissue Chip for Drug Screening program to improve ways of predicting drug safety and effectiveness. Researchers will collaborate over three years to refine existing 3-D human tissue chips and combine them into an integrated system that can mimic the complex functions of the h dunk high nike uman body.Led by the National Center for Advancing Translational Sciences (NCATS), the program will support 11 institu yeezy chaussure tions at $17 million in 2014 with additional support over the remaining two years if funds are available.Because these tissue chip systems will closely mimic human function, scientists can probe the tissue chips in ways that they aren鈥檛 able to d nike jordan4 o in people, and the knowledge gained may provide critical clues to disease progression and insights into the development of potential therapeutics.Fifteen NIH Institutes and Centers are involved in the coordination of this program. Current funding is being provided by NCATS, KARACHI:The rupee remained stable against the dollar at 104.4/104.6 in the inter-bank market on Monday compared to Friday鈥檚 close of 104.4/104.6.The currency market has fluctuated regularly in recent months with hefty rises and falls on some occasions. In the long run, however, the rupee has stood firm after experiencing extensive volatility, when it weakened from around Rs98 to a dollar to nb 530 above Rs103 in the wake of political impasse over alleged election rigging.Earlier, the rupee remained glued to the Rs98 level for months, recovering from the historic low of Rs110. It came under pressure following heavy debt repayme stanley cup nts to the International Monetary Fund (IMF) and other creditors, which ate into the central bank鈥檚 forei adidas campus 80s gn currency reserves. In 2013-14, the reserves, however, swelled more than 50%, thanks to IMF and other assistance and growing remittances sent home by overseas Pakistanis. 聽Published in The Express Tribune, February 14th, 2017.Like聽Business on Facebook, follow @Tribu

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ChemBridge Corp baskets yeezy oration has announced new multi-year research collaboration in discovery chemistry with AstraZeneca. This new alliance follows the previous collaboration between ChemBridge and AstraZeneca that was established in 2006 and successfully completed earlier this year ahead of schedule.In accordance with the new agreement scientists from ChemBridge and AstraZeneca will work together to design and develop a n yeezy ew generation of highly advanced, research intensive small molecule libraries that further enhance AstraZeneca's global drug discovery effort. Further details and financial terms were not disclosed."We are very pleased to enhance and extend our strategic relationship with AstraZeneca, one of the world's leading pharmaceutical companies, and to continue to build upon our track record of successful teamwork with AstraZeneca," said Eugene Vaisberg, Chairman and CEO of ChemBridge Corporation and ChemBridge Research nike dunk sb Laboratories, Inc. (CRL)."This major new deal, which is focused KARACHI:The country鈥檚 top eight departmental sides are set to vie it out for the 50-over National One Day Cup for departments that is set to begin in Karachi and Islamabad from Saturday.The eight sides 鈥?HBL, WAPDA, S adidas campus blu NGPL, SSGC, KRL, NBP, UBL and PIA 鈥?will play seven group games apiece, before the top two teams clash in the final.The tournament is currently being shared by Islamabad and NBP after the final was washed out due to rain without a ball being bowled.Salman Butt, Kamran Akmal eye national team call-upThis time around, the uggs hausschuhe Pakistan Cricket Board (PCB) has divided the tournament into two parts 鈥?the first will be p stanley layed between the departments while the second will be played between the regional sides.Joint-winners NBP, currently led by Qaiser Abbas, are confident of going the distance once again, especially with Nasir Jamshed set to make a return. 鈥淲e are confident of defending the title,鈥?said Abbas. 鈥淛amshed might return and join the team, which will give out batting a boos

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Link Technologies Limitedand the PNA Inventor Group have entered into a non-exclusive licence agreement to allow Link Technologies to manufacture and sell monomers for peptide nucleic acid (PNA) synthesis worldwide under the PNA Inventor Group鈥檚 patents.Financial details have not been disclosed. PNAs have numerous identified and proposed applications in molecular biology procedures, diagnostic assays, as well as antisense and anti-gene therapies.In terms of the overall research market for PNA-technologies, recent estimates predict that PNA synthesis will account for 10% of the global DNA synthesis market by 2010; a market presently worth US$800m and growing at ove adidas yeezy r 10% per year.Peter Nielsen, Professor at the University of Copenhagen, sp air force schwarz eaking on behalf of the PNA Inventor Group converse said, 鈥淲e are very pleased to have granted Link a license to make and sell PNA monomers. We look forward to cooperating with Link and are confident that the continued availability of high quality PNA monomers w KARACHI:The Sindh High Court (SHC) set aside on Friday a 21-year imprisonment handed down to a said to be political activist in an arms and explosives case.A two-judge bench, headed adidas campus rosa by Justice Muhammad Iqbal Kalhoro, remanded the case back to the ATC-IX judge with direction adidas campus rose to retry the suspect within a month.Last year, the suspect, Muhammad Rehan Hussain alias Bihari Hitman, was sentenced to a collective sentence of 21 years in explosives and illicit weapon cases.On July 12 last year, the ATC judge found Hussain guilty of carrying explosive material and unlicensed w new balance mujer eapons.Wrongly convicted: Top court frees man after 14 years 聽聽聽Rangers had claimed to have arrested him from Surjani Town area in September, 2016.The trial court had handed down 14 years of imprisonment to him in the explosives case and seven years in the illicit weapons case and also imposed a fine on him. However, the court ordered that both sentences will run concurrently.According to the prosecution, the Rangers had pi

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MIT engineers have genetically reprogrammed a strain of yeast so that it converts sugars to fats much more efficiently, an advance that could make possible the renewable production of high-energy fuels such as diesel. The researchers, led by Gregory Stephanopoulos, the Willard Henry Dow Professor of Chemical Engineering and Biotechnology at MIT, modified the metabolic pathways of yeast that naturally produce large quantities of lipids, to make them about 30 percent more efficient.鈥淲e have rewired the metabolism of these microbes to make them capable of producing oils at very high yields,鈥?yeezy 500 says Stephanopoulos, who is the sen dunk nike high ior author of the study. This upgrade could make the production of renewable high-energy fuels economically feasible, and the MIT team is now working on additional improvements that would help get even closer to that goal.鈥淲hat we鈥檝e done is reach about 75 percent of this yeast鈥檚 potential, and there is an additional 25 per dunks cent that will be subject of follow-up work, ISLAMABAD:A judicial magistrate on Saturday rejected bail applications of a man and two of his sons who had been arrested for allegedly beating up a court bailiff.Muhammad Eitibar, Muhammad Iftikhar Raza and Muhammad Bilal had been arrested by Karachi Company police after they obstructed and beat up a court official in Sector G-9 on October 30.Muhammad I adidas campus pink shfaq, the bailiff, had taken a man to meet his children in a family case in Sector G-9 where he was accosted and severely beaten up by the suspects.Ishfaq sustained injuries and a case against the trio was registered based on a medical report of Pims.Arrested for threatening a public servant Judicial Magistrate Jawad Hussain Adil sent them t adidas campus femme o Adiala Jail on judicial remand adidas samba og .Published in The Express Tribune, November 6th, 2016.

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When someone is suspected of criminal activity, one of the most important questions they are asked is if they have a credible alibi. Playing back past events in our minds, however, is not like playing back a video recording. Recollections of locations, dates, and companions can become muddled with the passage of time. If a suspect's memories are out of line with documented events, yeezy schuh a once-plausible alibi can crumble and may nb sneakers 574 be seen as evidence of guilt.To put people's memories of past whereabouts to the test, a team of researchers tracked the locations of 51 volunteers for one month and found that their recollections were wrong approximately 36% of the time."This is the first study to examine memory for where an e yeezy boost vent happened," said Simon J. Dennis, director of the Complex Human Data Hub at the University of Melbourne's School of Psychological Sciences and lead author of the study, which was published in the journalPsychological Science. "We were able to use experience-sampling methods The US constitution is the longest surviving constitution in the world. Drafted for a democracy, it provides for the separation of power between the executive, legislature and judiciary to ensure accountability and check misuse of power. This separatio ugg n of powers between the three pillars of state is fortunately enough, also present zapatillas nb in the constitution of Pakistan.The legislature and executive have for the most part of our history remained on the same team. Our legislature is not known to exer campus adidas beige cise its check over the executive. A legislator voting on any issue independently of the party鈥檚 stance is rare. As for the opposition, it has often been accused of being a 鈥榝riendly opposition鈥?This esprit de corps that exists between the executive and the legislature is, however, absent between the executive and the judiciary; exactly how it is principally supposed to be. Historically, in Pakistan it has been the executive that has always one-upped the judiciary. The attack on the Supreme Court

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Your next trendy h yeezys schuhe andbag could be fashioned from 鈥渓eather鈥?made from a fungus. Today, researchers will describe how they have harnessed this organism to convert food waste into sustainable faux leather, as well as paper products and cotton substitutes, with properties comparable to the tradition jordan al materials. They explain that this fungal leather takes less time to produce than existing substitutes already on the market, and, unlike some, is 100% biobased. The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2022 is a hybrid meeting being held virtually and in-person March 20-24, with on-demand access available March 21-April 8. The meeting features more than 12,000 presentations on a wide range of science topics. Cotton is in short supply, and, like petroleum-base dunk nike d textiles and leather, its production is associated with environmental concerns. Meanwhile, plenty of food goes to waste. Akram Zamani, Ph.D., set out to re KARACHI:Sindh and its heritage are in trouble. There is little help to save heritage si new balance uomo tes from damage, both natural and man-made, nor are people willing to come forward to help. If these sites are not preserved, Sindh鈥檚 heritage will be lost to the next generat nb balance ion.However, there i new balance 480 s one institution working towards the protection and preservation of our history 鈥?the Endowment Fund Trust. At an event, 鈥楽aving Sindh's Heritage鈥? held on Thursday evening at the Karachi Press Club (KPC) speakers discussed the need to safeguard the province鈥檚 heritage."The trust is doing a marvellous job saving Sindh's heritage. The trust recently came forward to help the press club for its renovation,鈥?said KPC President Siraj Ahmed.Culture dept wants inclusion of music, performing art institute in budget"Under the tenure of chief minister] Abdullah Shah in 1994 a law was passed called the Protected Heritage Act, in which it was said that Sindh's heritage must be saved and conserved,鈥?explained End

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To understand the progression of complex diseases such as ca jordans damen ncer, scientists have had to tease out the interactions between cells at progressively finer scales 鈥?from the behavior of a single tumor cell in the body on down to the activity of that cell鈥檚 inner machinery.To foster such discoveries, mechanical engineers at MIT are asics gel 1130 designing tools to image and analyze cellular dynamics at the micro- and nanoscale. Such tools, including microfluidics, membrane technology and metamaterials, may help scientists better characterize and develop therapies for cancer and other complex diseases. New medical discoveries depend on engineering advances in real-time, multifunctional imaging and quantitative analysis, says Nicholas Fang, an associate professor of mechanical engineering. 鈥淲hat we鈥檝e learned so far is more or less the architecture of cells, and th new balances 530 e next layer is the dynamics of cells,鈥?says Fang, who is developing optical sensors to illuminate individual components within a cell. 鈥淐ells KARACHI:Pakistan Cricket Board (PCB)聽finalised on Tuesday its coaching team for their England tour, appointing Australian Steve Rixon to lift their dwindling fielding standards.Rixon was appointed on the recommendation of head coach Mickey Arthur, who was bro ugg ultra mini ught in last month after Pakistan's disastrous World Twenty20 in India where it failed to reach the semi-finals.Arthur replaces Waqar Younis, who resigned in April.Pakistan in April appointed former captain Inzamam-ul-Haq as chief selector as they look to improve their rankings in one-day and Twenty20 internationals.BCCI receives 57 applications for head coach positionA Pakistan Cricket Board spokesman said: "We have appointed Rixon as fielding coach, Mushtaq Ahmed as bowling adidas campus coach for Tests, Azhar Mahmood (bowling coach) for the limited over series," said the spokesman.Rixon, 62, is regarded as a hard taskmaster and Arthur said last week the team's fielding was "in need of a huge lift".Pa stanleycup kistan leave for England on June 18 and wil

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While taking in the scenery during long road trips, passengers also may be taking in potentially harmful ultrafine particles (UFPs) that come into the car through outdoor air vents. Closing the vents reduces UFPs, but causes exhaled carbon dioxide to build up.Now, scientists report in the ACS journal Environmental Science & Technology that installing a newly developed high-efficiency cabin air filter (HECA) could reduce UFP exposure by 93 percent and keep carbon dioxide levels low.Yifang Zhu and Eon Lee explain that most modern cars come with cabin air filters, but they only block 40-60 percent of the UFPs when in 鈥渙utdoor air mo nike air force1 de.鈥?These particles are 100 nanometers or less in diameter; about a thousand of them could fit across the width of a human hai yeezys r.Studies suggest that UFPs, which are found in automotive exhaust, may be linked with health problems. Switching the venting sy yeezy sandales stem into 鈥渞ecirculation mode鈥?reduces UFPs by 90 percent, but because the interior is closed off from t KARACHI:If Sindh IG Allah Dino Khawaja is pointing to the Muttahida Qaumi Movement (MQM) or its workers as those responsible for killing police officials, the police should reveal the details of arrests and cases registered for the targeted killings of policemen as well as the convictions.This demand was made by MQM-Pakistan Rabita Com adidas campus verdi mittee member Faisal Subzwari during a press conference in PIB Colony on Friday. He rejected the allegations levelled against the party by the IG. A few days ago, Khawaja had, while addressing the business community, talked about how the police officials who participated in the Karachi operations in the 1990s were killed in 鈥榬evenge鈥? He added that the patrons of the target killers are sitting in assemblies.The MQM leader stated that if the IG implied that party workers had killed the said police officials, the party demands that the killers be arrested, adding that the adidas original campus police should e ugg mini xplain why they have been unable to arrest the killers so far.Subzwari,